Children have been treated with anti-inflammatory treatment, including parenteral immunoglobulin and steroids. 13-15 Initial hypotheses are that this syndrome may be related to COVID-19 based on initial laboratory testing showing positive serology in a majority of patients.
LS CHILD MODEL COLLECTION SERIES
Case reports and small series have described a presentation of acute illness accompanied by a hyperinflammatory syndrome, leading to multiorgan failure and shock. Recently, however, reports from Europe and North America have described clusters of children and adolescents requiring admission to intensive care units with a multisystem inflammatory condition with some features similar to those of Kawasaki disease and toxic shock syndrome. Among 345 children with laboratory-confirmed COVID-19 and complete information about underlying conditions, 23% had an underlying condition, with chronic lung disease (including asthma), cardiovascular disease, and immunosuppression most commonly reported. 7 Robust evidence associating underlying conditions with severe illness in children is still lacking. Relatively few cases of infants confirmed to have COVID-19 have been reported those who are infected have experienced mild illness. 1-4 Limited data describe clinical manifestations of COVID-19 that are generally milder in children compared with adults, 5-8 but also show that some children do require hospitalization and intensive care.
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![ls child model collection ls child model collection](https://i.pinimg.com/originals/65/04/9f/65049f0ab87ecb4baa92e04268b6482e.jpg)
The risk of severe disease and death has been highest in older people and in persons with underlying noncommunicable diseases (NCDs), such as hypertension, cardiac disease, chronic lung disease and cancer. As of, more than 4 million confirmed cases of COVID-19, including more than 285 000 deaths have been reported to WHO.